Hepatic Src Homology Phosphatase 2 Regulates Energy Balance in Mice

The Src homology 2 domain-containing protein-tyrosine phosphatase Src homology phosphatase 2 (Shp2) is a negative regulator of hepatic insulin action in mice fed regular chow. To investigate the role of hepatic Shp2 in lipid metabolism and energy balance, we determined the metabolic effects of its d...

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Hlavní autoři: Nagata, Naoto, Matsuo, Kosuke, Bettaieb, Ahmed, Bakke, Jesse, Matsuo, Izumi, Graham, James, Xi, Yannan, Liu, Siming, Tomilov, Alexey, Tomilova, Natalia, Gray, Susan, Jung, Dae Young, Ramsey, Jon J., Kim, Jason K., Cortopassi, Gino, Havel, Peter J., Haj, Fawaz G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Energy Balance-Obesity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380313/
https://ncbi.nlm.nih.gov/pubmed/22619361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1406
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