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Antiaging Gene Klotho Enhances Glucose-Induced Insulin Secretion by Up-Regulating Plasma Membrane Levels of TRPV2 in MIN6 β-Cells
Klotho is a recently discovered antiaging gene. Klotho is expressed in mouse pancreatic islets and in insulinoma β-cells (MIN6 β-cells). The purpose of this study was to investigate whether Klotho plays a role in the regulation of insulin secretion in MIN6 β-cells by overexpression and silencing of...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Endocrine Society
2012
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380305/ https://ncbi.nlm.nih.gov/pubmed/22597535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1091 |
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