Llwytho...

Molecular Mechanisms of Estrogen Receptors' Suppression of Lipogenesis in Pancreatic β-Cells

The gonadal steroid, 17β-estradiol (E2), suppresses pancreatic islet fatty acid and glycerolipid synthesis and prevents β-cell failure in rodent models of type 2 diabetes. β-Cell estrogen receptors (ER) mediate these actions by suppressing the expression and enzymatic activity of fatty acid synthase...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tiano, Joseph P., Mauvais-Jarvis, Franck
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380304/
https://ncbi.nlm.nih.gov/pubmed/22564979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1980
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