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Rapid, nongenomic estrogen actions protect pancreatic islet survival
The gonadal steroid, 17β-estradiol (E(2)), acts as a protective hormone preventing β-cell apoptosis in vivo in mice of both sexes and in cultured mouse and human islets. E(2) signals via the classical estrogen receptor (ER)α and ERβ, an extranuclear form of ERα and the G protein-coupled estrogen rec...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903892/ https://ncbi.nlm.nih.gov/pubmed/20634925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.1.3.9781 |
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