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Rapid, nongenomic estrogen actions protect pancreatic islet survival

The gonadal steroid, 17β-estradiol (E(2)), acts as a protective hormone preventing β-cell apoptosis in vivo in mice of both sexes and in cultured mouse and human islets. E(2) signals via the classical estrogen receptor (ER)α and ERβ, an extranuclear form of ERα and the G protein-coupled estrogen rec...

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Bibliografski detalji
Glavni autori: Liu, Suhuan, Mauvais-Jarvis, Franck
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903892/
https://ncbi.nlm.nih.gov/pubmed/20634925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.1.3.9781
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