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Regulator of G-Protein Signaling–5 Inhibits Bronchial Smooth Muscle Contraction in Severe Asthma

Severe asthma is associated with fixed airway obstruction attributable to inflammation, copious luminal mucus, and increased airway smooth muscle (ASM) mass. Paradoxically, studies demonstrated that the hypertrophic and hyperplastic ASM characteristic of severe asthma has reduced contractile capacit...

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Autori principali: Yang, Zhao, Balenga, Nariman, Cooper, Philip R., Damera, Gautam, Edwards, Richard, Brightling, Christopher E., Panettieri, Reynold A., Druey, Kirk M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380291/
https://ncbi.nlm.nih.gov/pubmed/22281988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0110OC
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