Role of Endoplasmic Reticulum Stress in Age-Related Susceptibility to Lung Fibrosis

The incidence of idiopathic pulmonary fibrosis (IPF) increases with age. The mechanisms that underlie the age-dependent risk for IPF are unknown. Based on studies that suggest an association of IPF and γherpesvirus infection, we infected young (2–3 mo) and old (≥18 mo) C57BL/6 mice with the murine γ...

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Hauptverfasser: Torres-González, Edilson, Bueno, Marta, Tanaka, Atsuko, Krug, Laurie T., Cheng, Dong-Sheng, Polosukhin, Vasiliy V., Sorescu, Dan, Lawson, William E., Blackwell, Timothy S., Rojas, Mauricio, Mora, Ana L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380287/
https://ncbi.nlm.nih.gov/pubmed/22227563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0224OC
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