Inhibition of NF-κB Signaling Reduces Virus Load and Gammaherpesvirus-Induced Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disorder of unknown etiology. Several studies have demonstrated an association between pulmonary infection with a herpesvirus and IPF. Based on those observations, we have developed a mouse model in which interferon (IFN)γR(−/−) mice...

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Bibliographische Detailangaben
Hauptverfasser: Krug, Laurie T., Torres-González, Edilson, Qin, Qianhong, Sorescu, Dan, Rojas, Mauricio, Stecenko, Arlene, Speck, Samuel H., Mora, Ana L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913377/
https://ncbi.nlm.nih.gov/pubmed/20566741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091122
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