Mitochondrial Oxidative Phosphorylation Is Impaired in Patients with Congenital Lipodystrophy

OBJECTIVE: Lipid accumulation in skeletal muscle and the liver is strongly implicated in the development of insulin resistance and type 2 diabetes, but the mechanisms underpinning fat accrual in these sites remain incompletely understood. Accumulating evidence of muscle mitochondrial dysfunction in...

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Hlavní autoři: Sleigh, Alison, Stears, Anna, Thackray, Kerrie, Watson, Laura, Gambineri, Alessandra, Nag, Sath, Campi, V. Irene, Schoenmakers, Nadia, Brage, Soren, Carpenter, T. Adrian, Murgatroyd, Peter R., O'Rahilly, Stephen, Kemp, Graham J., Savage, David B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
JCEM Online: Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380089/
https://ncbi.nlm.nih.gov/pubmed/22238385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-2587
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