Mitochondrial dysfunction in patients with primary congenital insulin resistance

Mitochondrial dysfunction is associated with insulin resistance and type 2 diabetes. It has thus been suggested that primary and/or genetic abnormalities in mitochondrial function may lead to accumulation of toxic lipid species in muscle and elsewhere, impairing insulin action on glucose metabolism....

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Bibliographische Detailangaben
Hauptverfasser: Sleigh, Alison, Raymond-Barker, Philippa, Thackray, Kerrie, Porter, David, Hatunic, Mensud, Vottero, Alessandra, Burren, Christine, Mitchell, Catherine, McIntyre, Martin, Brage, Soren, Carpenter, T. Adrian, Murgatroyd, Peter R., Brindle, Kevin M., Kemp, Graham J., O’Rahilly, Stephen, Semple, Robert K., Savage, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2011
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104774/
https://ncbi.nlm.nih.gov/pubmed/21555852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46405
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