ZnT8 Is a Major CD8(+) T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes

Type 1 diabetes results from the destruction of β-cells by an autoimmune T-cell response assisted by antigen-presenting B cells producing autoantibodies. CD8(+) T-cell responses against islet cell antigens, thought to play a central role in diabetes pathogenesis, can be monitored using enzyme-linked...

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Detaylı Bibliyografya
Asıl Yazarlar: Énée, Émmanuelle, Kratzer, Roland, Arnoux, Jean-Baptiste, Barilleau, Emilie, Hamel, Yamina, Marchi, Christophe, Beltrand, Jacques, Michaud, Bénédicte, Chatenoud, Lucienne, Robert, Jean-Jacques, van Endert, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2012
Konular:
Immunology and Transplantation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379659/
https://ncbi.nlm.nih.gov/pubmed/22586580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0071
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