Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target

Release of the malaria merozoite from its host erythrocyte (egress) and invasion of a fresh cell are crucial steps in the life cycle of the malaria pathogen. Subtilisin-like protease 1 (SUB1) is a parasite serine protease implicated in both processes. In the most dangerous human malarial species, Pl...

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Detalhes bibliográficos
Main Authors: Withers-Martinez, Chrislaine, Suarez, Catherine, Fulle, Simone, Kher, Samir, Penzo, Maria, Ebejer, Jean-Paul, Koussis, Kostas, Hackett, Fiona, Jirgensons, Aigars, Finn, Paul, Blackman, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378952/
https://ncbi.nlm.nih.gov/pubmed/22543039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2012.04.005
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