Wird geladen...

Anti-HIV-1 Activity of the Neurokinin-1 Receptor Antagonist Aprepitant and Synergistic Interactions with other Antiretrovirals

OBJECTIVES: Neurokinin-1 receptor (NK1R) antagonists interfere with binding of neuropeptide substance P (SP) to NK1R and exhibit novel anti-HIV-1 activities. Since NK1R antagonists effectively penetrate the blood-brain barrier to reduce the inflammatory response within the brain, we wished to evalua...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MANAK, Mark M., MOSHKOFF, Dmitry A., NGUYEN, Lequan T., MESHKI, John, TEBAS, Pablo, TULUC, Florin, DOUGLAS, Steven D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378647/
https://ncbi.nlm.nih.gov/pubmed/20975512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283405c33
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!