Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the transgenic (mRen2) rat

Angiotensin II contributes to myocardial tissue remodeling and interstitial fibrosis through NADPH oxidase-mediated generation of oxidative stress in the progression of heart failure. Recent data have suggested that nebivolol, a third-generation β-blocker, improves diastolic dysfunction by targeting...

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Autores principales: Ma, Lixin, Gul, Rukhsana, Habibi, Javad, Yang, Ming, Pulakat, Lakshmi, Whaley-Connell, Adam, Ferrario, Carlos M., Sowers, James R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2012
Materias:
Integrative Cardiovascular Physiology and Pathophysiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378296/
https://ncbi.nlm.nih.gov/pubmed/22447938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01126.2011
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