Deletion of prolyl carboxypeptidase attenuates the metabolic effects of diet-induced obesity

α-Melanocyte-stimulating hormone (α-MSH) is a critical regulator of energy metabolism. Prolyl carboxypeptidase (PRCP) is an enzyme responsible for its degradation and inactivation. PRCP-null mice (PRCP(gt/gt)) showed elevated levels of brain α-MSH, reduced food intake, and a leaner phenotype compare...

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Detaylı Bibliyografya
Asıl Yazarlar: Jeong, Jin Kwon, Szabo, Gyorgyi, Raso, Giuseppina Mattace, Meli, Rosaria, Diano, Sabrina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378159/
https://ncbi.nlm.nih.gov/pubmed/22454290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00544.2011
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