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Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1α in non-small cell lung cancer cells

Recent studies have established that amplification of the MET proto-oncogene can cause resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) cell lines with EGFR-activating mutations. The role of non-amplified MET in EGFR-depend...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xu, L, Nilsson, MB, Saintigny, P, Cascone, T, Herynk, MH, Du, Z, Nikolinakos, PG, Yang, Y, Prudkin, L, Liu, D, Lee, JJ, Johnson, FM, Wong, K-K, Girard, L, Gazdar, AF, Minna, JD, Kurie, JM, Wistuba, II, Heymach, JV
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378055/
https://ncbi.nlm.nih.gov/pubmed/20154724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.16
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