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IL-27 Inhibits OSM-mediated TNF-α and iNOS Gene Expression in Microglia
Elevated levels of Oncostatin M (OSM), an interleukin-6 family cytokine, have been observed in Multiple Sclerosis (MS), HIV-associated Neurocognitive Disorder (HAND) and glioblastoma (GBM); however, its effects within the CNS are not well understood. OSM regulates gene expression primarily by activa...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378052/ https://ncbi.nlm.nih.gov/pubmed/20468050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20989 |
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