Plasmacytoid Dendritic Cells Are Productively Infected And Activated Through TLR-7 Early After Arenavirus Infection

The antiviral response is largely mediated by dendritic cells (DC), including conventional (c) DCs that function as antigen presenting cells and plasmacytoid (p) DCs that produce Type I interferons, making them an attractive target for viruses. We find that the Old-world arenaviruses lymphocytic cho...

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Detalhes bibliográficos
Main Authors: Macal, Monica, Lewis, Gavin M., Kunz, Stefan, Flavell, Richard, Harker, James A., Zuñiga, Elina I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377983/
https://ncbi.nlm.nih.gov/pubmed/22704622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.04.017
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