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Constitutive but Not Inducible Attenuation of Transforming Growth Factor β Signaling Increases Natural Killer Cell Responses without Directly Affecting Dendritic Cells Early after Persistent Viral Infection

Rapid innate responses to viral encounters are crucial to shaping the outcome of infection, from viral clearance to persistence. Transforming growth factor β (TGF-β) is a potent immune suppressor that is upregulated early upon viral infection and maintained during chronic infections in both mice and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lewis, Gavin M., Macal, Monica, Hesser, Charles R., Zuñiga, Elina I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337531/
https://ncbi.nlm.nih.gov/pubmed/25589641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03076-14
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