Transgenic Overexpression of the Type I Isoform of Neuregulin 1 Affects Working Memory and Hippocampal Oscillations but not Long-term Potentiation

Neuregulin 1 (NRG1) is a growth factor involved in neurodevelopment and plasticity. It is a schizophrenia candidate gene, and hippocampal expression of the NRG1 type I isoform is increased in the disorder. We have studied transgenic mice overexpressing NRG1 type I (NRG1(tg-type I)) and their wild-ty...

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Hauptverfasser: Deakin, Inga H., Nissen, Wiebke, Law, Amanda J., Lane, Tracy, Kanso, Riam, Schwab, Markus H., Nave, Klaus-Armin, Lamsa, Karri P., Paulsen, Ole, Bannerman, David M., Harrison, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377963/
https://ncbi.nlm.nih.gov/pubmed/21878485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhr223
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