Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor–Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK

Hypofunction of N-methyl-d-aspartate receptors (NMDARs) in inhibitory GABAergic interneurons is implicated in the pathophysiology of schizophrenia (SZ), a heritable disorder with many susceptibility genes. However, it is still unclear how SZ risk genes interfere with NMDAR-mediated synaptic transmis...

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Foilsithe in:eNeuro
Main Authors: Kotzadimitriou, Dimitrios, Nissen, Wiebke, Paizs, Melinda, Newton, Kathryn, Harrison, Paul J., Paulsen, Ole, Lamsa, Karri
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2018
Ábhair:
New Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938717/
https://ncbi.nlm.nih.gov/pubmed/29740596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0418-17.2018
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