Minor Protease Inhibitor Mutations at Baseline Do Not Increase the Risk for a Virological Failure in HIV-1 Subtype B Infected Patients

BACKGROUND: Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findings in a larger cohort is essential. METHODS: To s...

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Main Authors: Scherrer, Alexandra U., Ledergerber, Bruno, von Wyl, Viktor, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Cellerai, Cristina, Furrer, Hansjakob, Calmy, Alexandra, Cavassini, Matthias, Elzi, Luigia, Vernazza, Pietro L., Bernasconi, Enos, Günthard, Huldrych F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377720/
https://ncbi.nlm.nih.gov/pubmed/22719859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037983
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