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Minor Protease Inhibitor Mutations at Baseline Do Not Increase the Risk for a Virological Failure in HIV-1 Subtype B Infected Patients

BACKGROUND: Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findings in a larger cohort is essential. METHODS: To s...

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主要な著者: Scherrer, Alexandra U., Ledergerber, Bruno, von Wyl, Viktor, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Cellerai, Cristina, Furrer, Hansjakob, Calmy, Alexandra, Cavassini, Matthias, Elzi, Luigia, Vernazza, Pietro L., Bernasconi, Enos, Günthard, Huldrych F.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377720/
https://ncbi.nlm.nih.gov/pubmed/22719859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037983
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