Minor Protease Inhibitor Mutations at Baseline Do Not Increase the Risk for a Virological Failure in HIV-1 Subtype B Infected Patients

BACKGROUND: Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findings in a larger cohort is essential. METHODS: To s...

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Hlavní autoři: Scherrer, Alexandra U., Ledergerber, Bruno, von Wyl, Viktor, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Cellerai, Cristina, Furrer, Hansjakob, Calmy, Alexandra, Cavassini, Matthias, Elzi, Luigia, Vernazza, Pietro L., Bernasconi, Enos, Günthard, Huldrych F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377720/
https://ncbi.nlm.nih.gov/pubmed/22719859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037983
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