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Could successful (mitochondrial) networking help prevent Huntington's disease?

Polyglutamine expansions in huntingtin (Htt) are known to cause the profound neurodegenerative disorder, Huntington's disease (HD). Mitochondrial dysfunction has long been implicated in the pathophysiology of HD, but the underlying mechanism remains obscure. An article by Costa et al in this mo...

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Autori principali: Oliveira, Jorge M A, Lightowlers, Robert N
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY-VCH Verlag 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377349/
https://ncbi.nlm.nih.gov/pubmed/21117121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201000104
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