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Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
Although a direct causative pathway from the gene mutation to the selective neostriatal neurodegeneration remains unclear in Huntington's disease (HD), one putative pathological mechanism reported to play a prominent role in the pathogenesis of this neurological disorder is mitochondrial dysfun...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947400/ https://ncbi.nlm.nih.gov/pubmed/20660112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq306 |
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