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Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

Although a direct causative pathway from the gene mutation to the selective neostriatal neurodegeneration remains unclear in Huntington's disease (HD), one putative pathological mechanism reported to play a prominent role in the pathogenesis of this neurological disorder is mitochondrial dysfun...

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Detalhes bibliográficos
Main Authors: Kim, Jinho, Moody, Jennifer P., Edgerly, Christina K., Bordiuk, Olivia L., Cormier, Kerry, Smith, Karen, Beal, M. Flint, Ferrante, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947400/
https://ncbi.nlm.nih.gov/pubmed/20660112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq306
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