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Virus infections in tumors pave the way for tumor-directed DC-vaccines

Effective treatment of solid cancers by tumor-directed DC-vaccines still remains a challenge in clinical oncology. For therapeutic success, knock-down of tumor-specific tolerance appears mandatory before a potent tumor-specific cytotoxic T-cell response can be triggered by DC-vaccinations. Evidence...

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Autori principali: Woller, Norman, Kühnel, Florian, Kubicka, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377008/
https://ncbi.nlm.nih.gov/pubmed/22720244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18099
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