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Tumor microenvironment in NSCLC suppresses NK cells function
NK cells, which contribute to tumor immunosurveillance, are present in the microenvironment of Non-Small-Cell Lung Carcinoma. However, they display strongly altered phenotype with decreased expression of NKp30, NKp80, DNAM-1, CD16 and ILT2, and impaired cytotoxic functions. The possible mechanisms l...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3377004/ https://ncbi.nlm.nih.gov/pubmed/22720258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18309 |
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