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Antibody-dependent cell cytotoxicity in monoclonal antibody-mediated tumor immunotherapy

Antibody-dependent cell cytotoxicity (ADCC) is critical in monoclonal antibody (mAb)-mediated cancer therapy. We recently showed that a tumor-specific mAb in combination with cyclophosphamide inhibited tumor cell growth and induced ADCC-synapses between tumor and effector cells in vivo, opening pers...

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Autors principals: Hubert, Pascale, Amigorena, Sebastian
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376972/
https://ncbi.nlm.nih.gov/pubmed/22720225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.1.17963
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