Antibody‐dependent Cytotoxicity Mediated by Chimeric Monoclonal Antibody Nd2 and Experimental Immunotherapy for Pancreatic Cancer

In a previous study, mouse monoclonal antibody (MoAb) Nd2 (m‐Nd2, mouse IgGl) labeled with (131) I exhibited efficacy in in vivo radioimmunotherapy against pancreatic cancer. In this study we prepared mouse/human chimeric antibody Nd2 (c‐Nd2, human IgG1) for clinical use and examined whether c‐Nd2 i...

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Gepubliceerd in:Jpn J Cancer Res
Hoofdauteurs: Nishihara, Tamahiro, Sawada, Tetsuji, Yamamoto, Atsushi, Yamashita, Yoshito, Ho, Jenny J. L., Kim, Young‐Sik, Chung, Kosei Hirakawa‐YS
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2000
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926427/
https://ncbi.nlm.nih.gov/pubmed/10965023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01019.x
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