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Chemoimmunomodulation of MDSCs as a novel strategy for cancer therapy
Tumor-induced myeloid-derived suppressor cells (MDSCs) are a critical barrier to effective immunotherapy of cancer. We identified that Docetaxel and a natural compound, Icariin, can target MDSCs with preferential apoptosis of M2 cells and polarization of the surviving cells towards M1 cells. Such st...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376962/ https://ncbi.nlm.nih.gov/pubmed/22720231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.1.18074 |
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