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Chemoimmunomodulation of MDSCs as a novel strategy for cancer therapy

Tumor-induced myeloid-derived suppressor cells (MDSCs) are a critical barrier to effective immunotherapy of cancer. We identified that Docetaxel and a natural compound, Icariin, can target MDSCs with preferential apoptosis of M2 cells and polarization of the surviving cells towards M1 cells. Such st...

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Bibliografische gegevens
Hoofdauteurs: Djeu, Julie, Wei, Sheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376962/
https://ncbi.nlm.nih.gov/pubmed/22720231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.1.18074
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