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GSTM1 and GSTT1 copy numbers and mRNA expression in lung cancer

Large fractions of the human population do not express GSTM1 and GSTT1 (GSTM1/T1) enzymes because of deletions in these genes. These variations affect xenobiotic metabolism and have been evaluated in relation to lung cancer risk, mostly based on null/present gene models. We measured GSTM1/T1 heteroz...

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Detalhes bibliográficos
Main Authors: Rotunno, Melissa, Lam, Tram K., Vogt, Aurelie, Bertazzi, Pier Alberto, Lubin, Jay, Caporaso, Neil E., Landi, Maria Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376678/
https://ncbi.nlm.nih.gov/pubmed/22392686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21890
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