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Multiplex PCR Detection of GSTM1, GSTT1, and GSTP1 Gene Variants : Simultaneously Detecting GSTM1 and GSTT1 Gene Copy Number and the Allelic Status of the GSTP1 Ile105Val Genetic Variant
The glutathione S-transferase (GST) genes GSTM1, GSTT1, and GSTP1 are involved in the detoxification of a broad range of toxic substances. Genetic polymorphisms in these genes have been studied intensively for their potential role in cancer susceptibility and drug response. In Caucasians, the enzyme...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Investigative Pathology
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2049057/ https://ncbi.nlm.nih.gov/pubmed/17916600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.070030 |
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