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Multiplex PCR Detection of GSTM1, GSTT1, and GSTP1 Gene Variants : Simultaneously Detecting GSTM1 and GSTT1 Gene Copy Number and the Allelic Status of the GSTP1 Ile105Val Genetic Variant

The glutathione S-transferase (GST) genes GSTM1, GSTT1, and GSTP1 are involved in the detoxification of a broad range of toxic substances. Genetic polymorphisms in these genes have been studied intensively for their potential role in cancer susceptibility and drug response. In Caucasians, the enzyme...

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Bibliografische gegevens
Hoofdauteurs: Buchard, Anders, Sanchez, Juan J., Dalhoff, Kim, Morling, Niels
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049057/
https://ncbi.nlm.nih.gov/pubmed/17916600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.070030
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