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GSTM1 and GSTT1 copy number variation in population-based studies of endometrial cancer risk

BACKGROUND: Glutathione S-transferases detoxify a broad range of carcinogenic metabolites and lack of GSTM1 and GSTT1 activity due to gene deletions are prevalent. The associations of GSTM1 and GSTT1 polymorphisms with endometrial cancer risk have been inconsistent. METHODS: We investigated gene-dos...

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Autors principals: Karageorgi, Stalo, Prescott, Jennifer, Wong, Jason Y.Y., Lee, I-Min, Buring, Julie E., De Vivo, Immaculata
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157698/
https://ncbi.nlm.nih.gov/pubmed/21558497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0190
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