Population-specific GSTM1 copy number variation

As one of the major glutathione conjugation enzymes, GSTM1 detoxifies a number of drugs and xenobiotics. Its expression and activity have been shown to correlate both with cancer risks and drug resistance. Through a genome-wide association study, we identified a significant association between HapMa...

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Autors principals: Huang, R. Stephanie, Chen, Peixian, Wisel, Steve, Duan, Shiwei, Zhang, Wei, Cook, Edwin H., Das, Soma, Cox, Nancy J., Dolan, M. Eileen
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
Associations Studies Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722188/
https://ncbi.nlm.nih.gov/pubmed/18948376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn345
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