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A General Method for Detecting Protease Activity via Gelation and its Application to Artificial Clotting

A modular system for detecting protease activity via enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficien...

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Bibliografski detalji
Glavni autori: Bremmer, Steven C., Chen, Jing, McNeil, Anne J., Soellner, Matthew B.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376645/
https://ncbi.nlm.nih.gov/pubmed/22538348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc31537h
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