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A General Method for Detecting Protease Activity via Gelation and its Application to Artificial Clotting
A modular system for detecting protease activity via enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficien...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376645/ https://ncbi.nlm.nih.gov/pubmed/22538348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc31537h |
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