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Enzyme-triggered Gelation: Targeting Proteases with Internal Cleavage Sites
A generalizable method for detecting protease activity via gelation is described. A recognition sequence is used to target the protease of interest while a second protease is used to remove the residual residues from the gelator scaffold. Using this approach, selective assays for both MMP-9 and PSA...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143987/ https://ncbi.nlm.nih.gov/pubmed/24394494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc48132h |
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