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Reducing Bias of Allele Frequency Estimates by Modeling SNP Genotype Data with Informative Missingness
The presence of missing single-nucleotide polymorphism (SNP) genotypes is common in genetic studies. For studies with low-density SNPs, the most commonly used approach to dealing with genotype missingness is to simply remove the observations with missing genotypes from the analyses. This naïve metho...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Research Foundation
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376470/ https://ncbi.nlm.nih.gov/pubmed/22719749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00107 |
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