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Growth Control by Committee – Intercellular Junctions, Cell Polarity, and the Cytoskeleton Regulate Hippo Signaling

Over the past decade, the Hippo tumor suppressor pathway has emerged as a central regulator of growth in epithelial tissues. Research in Drosophila and in mammals has shown that this kinase signaling cascade regulates the activity of the transcriptional coactivator and oncoprotein Yorkie/Yap. In thi...

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Detalhes bibliográficos
Main Authors: Boggiano, Julian C., Fehon, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376383/
https://ncbi.nlm.nih.gov/pubmed/22516196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.03.013
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