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Growth Control by Committee – Intercellular Junctions, Cell Polarity, and the Cytoskeleton Regulate Hippo Signaling
Over the past decade, the Hippo tumor suppressor pathway has emerged as a central regulator of growth in epithelial tissues. Research in Drosophila and in mammals has shown that this kinase signaling cascade regulates the activity of the transcriptional coactivator and oncoprotein Yorkie/Yap. In thi...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376383/ https://ncbi.nlm.nih.gov/pubmed/22516196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.03.013 |
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