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Improved insulin sensitivity after treatment of PPARγ and PPARα ligands is mediated by genetically modulated transcripts

OBJECTIVES: We aimed to define effects of PPARγ and PPARα agonist mono and combination therapy on adipose tissue and skeletal muscle gene expression in relation to insulin sensitivity. We further investigated the role of genetic polymorphisms in PPAR ligand-modulated genes in transcriptional regulat...

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Detalhes bibliográficos
Main Authors: Rasouli, Neda, Kern, Philip A., Elbein, Steven C., Sharma, Neeraj K., Das, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376224/
https://ncbi.nlm.nih.gov/pubmed/22437669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328352a72e
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