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Improved insulin sensitivity after treatment of PPARγ and PPARα ligands is mediated by genetically modulated transcripts

OBJECTIVES: We aimed to define effects of PPARγ and PPARα agonist mono and combination therapy on adipose tissue and skeletal muscle gene expression in relation to insulin sensitivity. We further investigated the role of genetic polymorphisms in PPAR ligand-modulated genes in transcriptional regulat...

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Main Authors: Rasouli, Neda, Kern, Philip A., Elbein, Steven C., Sharma, Neeraj K., Das, Swapan K.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376224/
https://ncbi.nlm.nih.gov/pubmed/22437669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328352a72e
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