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Grp1 plays a key role in linking insulin signaling to glut4 recycling
The glucose transporter type 4 (glut4) is critical for metabolic homeostasis. Insulin regulates glut4 by modulating its expression on the cell surface. This regulation is achieved mainly by targeting the endocytic recycling of glut4. We identify Grp1 (general receptor for 3-phosphoinositides 1) as a...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376201/ https://ncbi.nlm.nih.gov/pubmed/22609160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.03.004 |
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