The hTERT Promoter Enhances the Antitumor Activity of an Oncolytic Adenovirus under a Hypoxic Microenvironment

Hypoxia is a microenvironmental factor that contributes to the invasion, progression and metastasis of tumor cells. Hypoxic tumor cells often show more resistance to conventional chemoradiotherapy than normoxic tumor cells, suggesting the requirement of novel antitumor therapies to efficiently elimi...

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Bibliografische gegevens
Hoofdauteurs: Hashimoto, Yuuri, Tazawa, Hiroshi, Teraishi, Fuminori, Kojima, Toru, Watanabe, Yuichi, Uno, Futoshi, Yano, Shuya, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376103/
https://ncbi.nlm.nih.gov/pubmed/22720091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039292
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