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Constriction of Retinal Arterioles to Endothelin-1: Requisite Role of Rho Kinase Independent of Protein Kinase C and L-Type Calcium Channels

PURPOSE. Although endothelin-1 (ET-1) is a potent vasoconstrictor peptide implicated in several retinal pathologies, the underlying mechanism of vasoconstriction is understood incompletely. We addressed this issue by assessing the contributions of extracellular calcium (Ca(2+)), L-type voltage-opera...

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Autors principals: Potts, Luke B., Ren, Yi, Lu, Guangrong, Kuo, Enoch, Ngo, Ellen, Kuo, Lih, Hein, Travis W.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376072/
https://ncbi.nlm.nih.gov/pubmed/22427601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9542
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