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Role of Endothelium in Vasomotor Responses to Endothelin System and Protein Kinase C Activation in Porcine Retinal Arterioles

PURPOSE. Endothelial cells synthesize vasodilator nitric oxide (NO) and vasoconstrictor endothelin-1 (ET-1) from NO synthase (eNOS) and endothelin-converting enzyme-1 (ECE-1), respectively. Protein kinase C (PKC) and Rho kinase (ROCK) are major signaling molecules mediating vasoconstriction. Althoug...

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Bibliografski detalji
Glavni autori: Potts, Luke B., Bradley, Patrick D., Xu, Wenjuan, Kuo, Lih, Hein, Travis W.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835269/
https://ncbi.nlm.nih.gov/pubmed/24243985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs13-13178
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