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Role of Arginase in Selective Impairment of Endothelium-Dependent Nitric Oxide Synthase-Mediated Dilation of Retinal Arterioles during Early Diabetes
PURPOSE: Retinal vasomotor activity can be regulated by two major endothelial enzymes, nitric oxide synthase (NOS) and cyclooxygenase (COX). The vascular arginase also consumes a NOS substrate and thus impedes NOS-mediated vasodilation. Diabetes mellitus exhibits vascular complications in the retina...
Tallennettuna:
| Julkaisussa: | Invest Ophthalmol Vis Sci |
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| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Association for Research in Vision and Ophthalmology
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7405695/ https://ncbi.nlm.nih.gov/pubmed/32437549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.5.36 |
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