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Constriction of Retinal Venules to Endothelin-1: Obligatory Roles of ET(A) Receptors, Extracellular Calcium Entry, and Rho Kinase

PURPOSE: Endothelin-1 (ET-1) is a potent vasoconstrictor peptide implicated in retinal venous pathologies such as diabetic retinopathy and retinal vein occlusion. However, underlying mechanisms contributing to venular constriction remain unknown. Thus, we examined the roles of ET-1 receptors, extrac...

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Bibliografiska uppgifter
I publikationen:Invest Ophthalmol Vis Sci
Huvudupphovsmän: Chen, Yen-Lin, Ren, Yi, Xu, Wenjuan, Rosa, Robert H., Kuo, Lih, Hein, Travis W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Association for Research in Vision and Ophthalmology 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203175/
https://ncbi.nlm.nih.gov/pubmed/30372743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-25369
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