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Depletion of p31(comet) Protein Promotes Sensitivity to Antimitotic Drugs

Antimitotic spindle poisons are among the most important chemotherapeutic agents available. However, precocious mitotic exit by mitotic slippage limits the cytotoxicity of spindle poisons. The MAD2-binding protein p31(comet) is implicated in silencing the spindle assembly checkpoint after all kineto...

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Detalhes bibliográficos
Main Authors: Ma, Hoi Tang, Chan, Yan Yan, Chen, Xiao, On, Kin Fan, Poon, Randy Y. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375577/
https://ncbi.nlm.nih.gov/pubmed/22544748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364356
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