Orderly Inactivation of the Key Checkpoint Protein Mitotic Arrest Deficient 2 (MAD2) during Mitotic Progression

Anaphase is promoted by the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C) only when all the chromosomes have achieved bipolar attachment to the mitotic spindles. Unattached kinetochores or the absence of tension between the paired kinetochores activates a surveillance mechanism terme...

Full description

Saved in:
Bibliographic Details
Main Authors: Ma, Hoi Tang, Poon, Randy Y. C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075651/
https://ncbi.nlm.nih.gov/pubmed/21335556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201897
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items